Selected Publications

Spenden & Helfen

Selected Publications of Prof. Dr. Lawrence Rajendran

  • Lawrence Rajendran*, Hans-Joachim Knolker and Kai Simons (2010) (*Corresponding author) Subcellular Targeting strategies for Drug Discovery and Delivery Nature Reviews Drug Discvovery epub 31 Dec 2009 (invited review)
  • Adriano Aguzzi* and Lawrence Rajendran* (2009) (*Corresponding authors) The transcellular spread of cytosolic amyloids, prions and prionoids Neuron 24 Dec 2009 (invited review)
  • Hermann-Josef Kaiser, Daniel Lingwood, Ilya Levental, Julio Sampaio, Lucie Kalvodova, Lawrence Rajendran, Kai Simons (2009)
  • Membrane probes reveal order relationships between lipid phases in model membranes and plasma membranes. Proc Natl Acad Sci U S A Sep 29, 106 (39): 16645-50
  • Zoë V. Goodger, Lawrence Rajendran, Bernhard M. Kohli, Ruth C. von Rotz, Roger M. Nitsch, Uwe
  • Konietzko (2009) Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic
  • pathway. J. Cell. Science Oct 15, 122: 3703-14
  • Lawrence Rajendran*, Julia Beckmann, Astrid Magenau, Katharina Gaus, Antonella viola, Bernd
  • Giebel and Harald Illges (2009) (*Corresponding author) The endocytic proteins, flotillins are involved in the polarization of leukocytes and hematopoietic stem cells PLOS one epub 22 Dec 2009
  • Lawrence Rajendran, Anja Schneider, Georg Schlechtingen, Sebastian Weidlich, Jonas Ries, Tobias Braxmeier, Petra Schwille, Jörg Schulz, Cornelia Schroeder, Mikael Simons, Gary Jennings, Hans-Joachim Knoelker, Kai Simons Efficient inhibition of the Alzheimer’s disease R-secretase by membrane targeting Science. Apr 25; 320(5875): 520-3 (2008)
  • Katarina Trajkovic, Chieh Hsu, Salvatore Chiantia, Lawrence Rajendran, Dirk Wenzel, Petra Schwille, Britta Brügger and Mikael Simons
  • A role for ceramide in exosome formation within multivesicular endosomes Science. Feb 29;319(5867):1244-7 (2008)
  • Anja Schneider*, Lawrence Rajendran*, Masanori Honsho, Gerald Donnert, Stefan W. Hell, Mikael Simons Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons. J Neurosci., 28 (11), 2874-2882 (2007) (* equal contribution)
  • Angelika Kippert, Katarina Trajkovic, Lawrence Rajendran, Jonas Ries, and Mikael Simons Rho regulates membrane transport in the endocytic pathway to control plasma membrane specialization in oligodendroglial cells. J Neurosci., 27, 3560-70. (2007)
  • Lawrence Rajendran and Kai Simons (2008) Membrane targeting and Trafficking in Alzheimer’s Disease, Foundation Ipsen Series (invited review)
  • Lawrence Rajendran and Kai Simons (2005) Lipid rafts and membrane dynamics. J. Cell Sci. 1099-102. (2005) (invited review)
  • Lawrence Rajendran*, Marlen Knobloch*, Kathrin D. Geiger, Stephanie Dienel, Roger Nitsch, Kai Simons, Uwe Konietzko Increased Abeta production leads to Intracellular Accumulation of Abeta in Flotillin-1-Positive Endosomes. Neurodegenerative Diseases.  4(2-3):164-70 (2007)
  • Lawrence Rajendran, Le Lay S, Illges H Raft association and lipid droplet targeting of flotillins are independent of caveolin.
  • Biol Chem. 388, 307-14 . (2007) (corresponding author)
  • Lawrence Rajendran, Honsho M, Zahn TR, Keller P, Geiger KD, Verkade P, Simons K. Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc Natl Acad Sci U S A, 103, 11172-7. (2006)
  • Lawrence Rajendran, Madhan Masilamani, Samuel Solomon, Ritva Tikkanen, Claudia A.O. Stuermer, Helmut Plattner and Harald Illges
  • Asymmetric localization of Flotillins in preassembled platforms confer inherent polarity to hematopoietic cells. Proc Natl Acad Sci U S A, 100, 8241-6. (2003)
  • Soeren Deininger, Lawrence Rajendran, Friedrich Lottspeich, Michael Przybylski, Harald Illges, Claudia A.O. Stuermer, and Alexander Reuter Identification of teleost Thy-1, association with non-caveolar lipid rafts defined by Reggie proteins and its localization to axon regenerating retinal ganglion cells. Mol Cell Neurosci., (2003) 22, 544-54.
  • Samuel Solomon, Madhan Masilamani, Lawrence Rajendran, Martin Bastmeyer, Claudia A.O. Stuermer, Harald Illges. The lipid raft microdomain-associated protein reggie-1/flotillin-2 is expressed in human B cells and localized at the plasma membrane and centrosome in PBMC. Immunobiology. 205, 108-19. (2002)
  • Reddy GB, Purnapatre K, Lawrence Rajendran, Roy S, Varshney U, Surolia A. Linear free-energy model description of the conformational stability of uracil-DNA glycosylase inhibitor – A thermodynamic characterization of interaction with denaturant and cold denaturation. Eur J Biochem. May;261(3):610-7. (1999)