Ausgewählte Publikationen von Dr. Melanie Meyer-Lühmann

  • 1. Koffee, R.M., Meyer-Luehmann, M., Hashimoto, T., Adams, K.W., Mielke, M.L., Garcia-Alloza, M., Micheva, K.D., Smith, S.J., Kim, M.L., Lee, V.M., Hyman, B.T., Spires-Jones, T.L. (2009). Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques. ProcNatlAcadSci 106 (10): 4012-7.
  • 2. Koenigsknecht-Talboo, J., Meyer-Luehmann, M., Parsadanian, M., Garcia-Alloza, M., Finn, M.B., Hyman, B.T., Bacskai, B.J. and Holtzman, D.M. (2008). Rapid microglial response around amyloid pathology after systemic anti-Abeta antibody administration in PDAPP mice. J Neurosci. 28(52):14156-64.
  • 3. Spires-Jones, T.L., Mielke, M.L., Rozkalne, A., Meyer-Luehmann, M., de Calignon, A., Bacskai, B.J., Schenk, D. and Hyman, B.T. (2008). Passive immunotherapy increases structural plasticity in a mouse model of Alzheimer disease. Neurobiol Dis. 2009 Feb;33(2):213-20. Epub 2008 Nov 6.
  • 4. Jones, P.B., Rozkalne, A., Meyer-Luehmann, M., Spires-Jones, T.L., Makarova, A., Kumar, A.T., Berezovska, O., Bacskai, B.J. and Hyman, B.T. (2008). Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy. J Biomed Opt 13 (1): 014008.
  • 5. Meyer-Luehmann, M., Spires-Jones, T.L., Prada, C., De Calignon, A., Rozkalne, A., Koenigsknecht-Talboo, J., Holtzman, D.M., Bacskai, B.J. and Hyman, B.T. (2008). Rapid appearance and local toxicity of amyloid plaques in a mouse model of Alzheimer’s disease. Nature 451, 720-4.
  • 6. Bolmont, T., Clavaguera, F., Meyer-Luehmann, M., Herzig, M.C., Radde, R., Staufenbiel, M., Lewis, J., Hutton, M., Tolnay, M. and Jucker, M. (2007). Induction of tau pathology by intracerebral infusion of amyloid-beta-containing brain extract and by amyloid in APP X tau transgenic mice. Am J Pathol 171, 2012-20.
  • 7. Spires-Jones, T.L., Meyer-Luehmann, M., Osetek, J.D., Jones, P.B., Stern, E.D., Bacskai, B.J. and Hyman, B.T. (2007). Impaired spine stability underlies plaque-related spine loss in an Alzheimer’s disease mouse model. Am J Pathol 171, 1304-11.
  • 8. Garcia-Alloza, M., Dodwell, S.A., Meyer-Luehmann, M., Hyman, B.T. and Bacskai, B.J. (2006). Plaque-derived oxidative stress mediates distorted neurite trajectories in the Alzheimer mouse model. J Neuropathol Exp Neurol 65, 1082-9.
  • 9. Meyer-Luehmann, M., Coomaraswamy, J., Bolmont, T., Kaeser, S., Schaefer, C., Kilger, E., Neuenschwander, A., Abramowski, D., Frey, P., Jaton, A.L., Vigouret, J.M., Paganetti, P., Walsh, D.M., Mathews, P.M., Ghiso, J., Staufenbiel, M., Walker, L.C. and Jucker, M. (2006). Induction of cerebral beta-amyloidogenesis is governed by agent and host. Science 313, 1781-4.
  • 10. Spires, T.L., Meyer-Luehmann, M., Stern, E.D., McLean, P.J., Skoch, J., Nguyen, P.T., Bacskai, B.J. and Hyman, B.T. (2005). Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy. J Neurosci 25, 7278-87.
  • 11. Sykova, E., Vorisek, I., Antonova, T., Mazel, T., Meyer-Luehmann, M., Jucker, M., Hajek, M., Or, M. and Bures, J. (2005). Changes in extracellular space size and geometry in APP23 transgenic mice: A model of Alzheimer’s disease. Proc Natl Acad Sci USA 102, 479-84.
  • 12. Mueggler, T., Meyer-Luehmann, M., Rausch, M., Staufenbiel, M., Jucker, M., and Rudin, M. (2004). Restricted diffusion in the brain of transgenic mice with cerebral amyloidosis. Eur J Neurosci 20, 811-7.
  • 13. Meyer-Luehmann, M., Stalder, M., Herzig, M. C., Kaeser, S. A., Kohler, E., Pfeifer, M., Boncristiano, S., Mathews, P. M., Mercken, M., Abramowski, D., Staufenbiel, M. and Jucker, M. (2003). Extracellular amyloid formation and associated pathology in neural grafts. Nat Neurosci 6, 370-377.
  • 14. Meyer-Luehmann, M., Thompson, J. F., Berridge, K. C., and Aldridge, J. W. (2002). Substantia nigra pars reticulata neurons code initiation of a serial pattern: implications for natural action sequences and sequential disorders. Eur J Neurosci 16, 1599-1608.


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